"The familial relationship between Alice and Bob is "second cousins once removed."

Here's why:

Bob's father is a cousin of Alice's father, which means that Bob's father and Alice's father are first cousins. That makes Bob and Alice second cousins to each other.

However, Bob is not in the same generation as Alice, because he is the child of one of Alice's second cousins (Bob's father). This means that there is a generational difference of one between Bob and Alice.

When there is a generational difference between two relatives, it is called a "removed" relationship. So, Bob is "once removed" from Alice in terms of their second cousin relationship. Therefore, the full familial relationship between Alice and Bob is "second cousins once removed."