Yes. Simply reasoned I think a weakened or compromised cell or organism that is stressed or deprived of energy will tend to weaken to expiration quicker than the strong. Higher rates of autophagy make more sense for a 5 day fast than intermittent which may allow hangers on to survive whether or not one believes if studies of either are conclusive. A 5 day FMD is kind of a hybrid but one will feel day 3 and 4 effects in a noticeable way. FMD 3 times/yr has been a good trade off for strict I/F for 350 days/ yr ( or less). Just 2 sats worth.