Yes. Part of the motivation behind relay sets is interest based relays, as you said.

Because a quick and easy relay toggle doesn’t exist yet we have not yet discovered if / how much a quick toggle gives you different content.

The relay sets example in the story is all pre-defined sets.

What if we inserted a bit of randomness and asked how can you completely change the perspective by minimizing relays that I use, users I follow, topics I frequent etc.