From a user point of view, why use multiple clients (maybe one for each platform) but beyond that, why??
Discussion
Because you will see up to 40% difference in the content in your feed and the difference is about to increase.
Like hsoc says, I feel it makes little difference to switch clients just to see the differential feed, especially if majority of the posts are going to be the same🤷 it's difficult to find the difference in feeds unless you spend a substantial time with a client (I'll try this 🙌)
But i still think it makes more sense to try multiple clients but only use 1 main client + occassional 1-2 clients depending on features + tool clients like nostrified/nosli/bookmark-viewer/listr as & when needed