Guilt most certainly is the communication of God regarding sin. Feeling sorry for your behavior is a good thing. Repenting for your sin is how guilt is removed.

They is a book called the Bible that has the testaments of those who have a direct relationship with God. Here is an example of the guilt from an action in the Old Testament and the remedy that is sanctioned regarding manslaughter.

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Deu 19:11-13 KJV ¶But if any man hate his neighbour, and lie in wait for him, and rise up against him, and smite him mortally that he die, and fleeth into one of these cities:

12. Then the elders of his city shall send and fetch him thence, and deliver him into the hand of the avenger of blood, that he may die.

13. Thine eye shall not pity him, but thou shalt put away the guilt of innocent blood from Israel, that it may go well with thee.

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Here is John The Baptist recommending repent (The remedial action of guilt):

Mat 3:1-3 KJV In those days came John the Baptist, preaching in the wilderness of Judea,

2. And saying, Repent ye: for the kingdom of heaven is at hand.

3. For this is he that was spoken of by the prophet Esaias, saying, The voice of one crying in the wilderness, Prepare ye the way of the Lord, make his paths straight.

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Luk 13:1-9 KJV There were present at that season some that told him of the Galileans, whose blood Pilate had mingled with their sacrifices.

2. And Jesus answering said unto them, Suppose ye that these Galileans were sinners above all the Galileans, because they suffered such things?

3. I tell you, Nay: but, except ye repent, ye shall all likewise perish.

4. Or those eighteen, upon whom the tower in Siloam fell, and slew them, think ye that they were sinners above all men that dwelt in Jerusalem?

5. I tell you, Nay: but, except ye repent, ye shall all likewise perish.

6. ¶He spake also this parable; A certain man had a fig tree planted in his vineyard; and he came and sought fruit thereon, and found none.

7. Then said he unto the dresser of his vineyard, Behold, these three years I come seeking fruit on this fig tree, and find none: cut it down; why cumbereth it the ground?

8. And he answering said unto him, Lord, let it alone this year also, till I shall dig about it, and dung it:

9. And if it bear fruit, well: and if not, then after that thou shalt cut it down.

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Sin most certainly is part of our character. There is no man, save the Son of God, Jesus Christ, who is without sin. Repentance is the antidote to sin and the side effect, guilt. Man without guilt is delusional and he like the fig tree that does not produce good fruit will be cut down and cast into the fire.

The Buddha encountered Mara who was Satan. The Buddha most certainly knew guilt as it was the motivator that led him to leave the life of comfort and go into retreat of the forest and wild.

Satan is the deceiver and he will do anything to make a man give up his opportunity to eternal life. This because Satan has been marked for eternal damnation. You as a human have free will and a choice. Without guilt you are incapable of understanding the negative affects of your actions.