So selective serotonin re-uptake inhibitors modify the concentration of serotonin in the brain synapses. The interesting thing is that over time your body will absorb the serotonin receptors decreasing the effect of the manipulated serotonin concentrations. The brain is a symphony of hormones, changing the volume of one instrument in the symphony (serotonin) doesn’t increase the quality of the music.

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Yup like any pharmas you build tolerance because your brain gets used to the drug and changes how it works in response.

This is why I just blaze now.