Based on the difference in average lifespan I would say men and women age differently. The difference is not solely based on propensity to engage in dangerous behaviors (such as working more dangerous jobs). I suspect part of it is due to iron accumulation in men. Considering that many of the stressors in our toxic world today are oxidative in nature, I think this compounds the effect that stored iron can have. So up until about 50 women have an advantage in getting rid of excess iron and so have less oxidative damage which I suspect has a substantial effect on aging. Along with the blood loss also being an additional way of getting rid of toxins. Note the above are what I think, but it would be difficult to validate with studies.
Discussion
Good reminder to donate blood regularly.
But wait,
How dare you!
Technically I do think a man could menstruate. Transplant a uterus into a man. Manipulate hormone levels to build up and then shed the endometrial lining. And by doing so the man would menstruate. But Lord help us if we get to a place where people start doing CRISPR of some sort to change all XY chromosomes to XX chromosomes. Some of the sequelae I've seen of these attempted "sex reassignment" surgeries are terrible. By the way, disagreement with AAMC standards for support of "gender affirming care" and DEI were the primary reasons for me leaving academic medicine.