The one I'm running came as a "plug and play" (lmao bullshit) but depending on the ecu model it should run most engines if you wire it correctly. I think the new one is called dropbear.

speeduino.com/home/about/features

Megasquirt is still better in a lot of ways but this is cheaper. I also keep forgetting to look into rusefi rusefi.com/

I'm unaware of anyone running a diesel with it. I'm pretty unfamiliar with diesels that aren't all mechanical.