You can't. If people see your post, they can reply.

If you block them you'll not see their reply but that's won't work en masse.

Welcome 💜 follow some more Plebs

Yeah this is an open platform. There isn’t a way to lock your profile down. At least not yet. I imagine a feature like that will be built in the future.

That’s the neat part. You don’t.

Welcome! We like to welcome new users here, don’t worry this is a friendly place (still).

welcome! 🫂💜

You can mute profiles that you don't like. But usually, they're just being polite and welcoming you. 🖖🏻👽