I don't want to see anything from npubs with no NIP-05 filled in:

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That would be a nice feature, but a NIP-05 is hardly an account verification because they are easy and cheap to set up. I think filtering by presence of nip-05 is a step toward filtering by "established" nip-05 servers and then we have a permissioned system.

It's cheap to setup, but still a hurdle regardless.

It's lame to see bots and reply guys on here

It is super lame. I would just hate to see clients only displaying notes from "approved" servers. I have wanted to block whole nip-05 servers, though (mostr-pub).

Agreed. And I would want all of this user controlled. A simple checkbox in this case