Reviewing the case, developmental biologist Emma Hilton noted on X that the toddler girl was “just about ready for a training bra. Normal for a 10-to-12-year-old.” She also noted that the toddler’s “uterus development was approaching Tanner stage 4. That’s period territory.” From the case study, it appears that the girl’s condition was reversed when the exposure to her father’s medication stopped.
“The hormone therapy of the father was changed from a gel to a transdermal patch, and the girl experienced regression of breast development, normalization of growth velocity, pelvic ultrasound and GnRH stimulation test,” reads the case study. Hilton, again posting to X, said that it may not be so simple: “And another note: his daughter’s precocious puberty ‘receded’ after exposure to estrogen was stopped. The assumption is that all is now ‘reset.’- I’d advocate caution there,” she wrote.
In another post, she told an X user that she is unsure if the girl will go on to experience a “normal” or “second” puberty, or if she will remain taller for her age. “I’m not sure there can be answer to that. It’s possibly unprecedented,” posted Hilton.
