P53 // GUARDIAN of the GENOME

Refers to the tumor suppressor protein p53, encoded by the TP53 gene. p53 plays a crucial role in maintaining genomic stability by regulating cell cycle progression, DNA repair, and apoptosis in response to DNA damage or cellular stress.

Tumor Suppressor:

p53 is a key component of the body's defense against cancer, as it helps prevent the development of tumors by stopping the proliferation of cells with damaged DNA.

DNA Damage Response:

When DNA is damaged, p53 activates various mechanisms to repair the damage, halt cell division, or trigger programmed cell death (apoptosis) if the damage is irreparable.

Cell Cycle Regulation:

p53 controls cell cycle checkpoints, ensuring that cells with damaged DNA do not proceed to the next stage of cell division, which could lead to the propagation of mutations.

Transcription Factor:

p53 acts as a transcription factor, binding to specific DNA sequences and regulating the expression of genes involved in DNA repair, apoptosis, and cell cycle arrest.

P53 can be weaponised as a potential "KILL SWITCH"

Using mRNA technology to deliberately suppress p53 – the body's core cancer defense – is biologically possible and would be catastrophic. By hiding malicious code in gene therapies (e.g., "next-gen vaccines"), attackers could disable cellular safeguards, causing aggressive cancers to emerge years later.

The true danger lies in rushed approvals during health crises, which might bypass safety audits.