Didn't they use to cure lumber bound for colonial ships with this stuff?

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Yes. I work in the industry. Creosote is only allowed in the railroad industry. Everywhere else it is banned.

I’m not sure if it’s exactly the same. If you get the creosote that’s used to treat lumber, on your skin, it will burn and scar you.

It looks like there is history of medicinal use of the oil derived from the plant (not coal tar)

https://www.texasbeyondhistory.net/ethnobot/images/creosote.html

Yeah there has to be a difference. No way it’s the creosote I know of.

No, I think that is a tar extracted from coal. This is the common name of a bush local to Arizona, also known as chaparral, greasewood, or Larrea tridentata