If you can, try to get him to reduce or ween off the steroids. For me the breathing problems are coming less frequently, but I've spent a couple years purposely breathing deep - like, I visualize it as breathing into my nuts - and it helps. Over time, I think natural cell replacement will reverse the damage. But steroids cause other problems.
Your sister's liver should rejuvenate - livers are great at healing, and heavy drinkers with severe liver damage can heal back to 100%.
I was actually originally against taking the vaccine, but I let other people's emotions influence me. My mom was frantic... She is probably the only person who can influence me like that.