The highly anticipated matchup between No. 4 Ohio State and No. 3 Penn State is set for Saturday, with both teams ranked in the top five for the first time since 1996. The Buckeyes have dominated the series, winning seven straight against the Nittany Lions, but Penn State's quarterback Drew Allar will be a game-time decision due to an apparent knee injury. Ohio State's offensive line is also dealing with injuries and uncertainty, which could lead to a defensive showdown. Both teams boast strong defenses, ranking top three in the Big Ten in total defense and scoring defense.

Source: https://www.cbssports.com/college-football/news/ohio-state-vs-penn-state-prediction-pick-spread-football-game-odds-where-to-watch-tv-channel-stream/