Wait, explain how you want to use it? You can connect your BTC pay server wallet to Zeus and control it that way. But if you're talking about using Zeus as the back end, I'm not exactly sure that's possible. I know you can open up a channel to the Zeus' LSP.....
Discussion
I was thinking of setting up Zeus like a LN node and then connect that to btcpayserver self host thing
Ahh yeah, I'm not sure that's possible. That probably would be a question, Zeus itself would have to answer. I think you have to use the Lightning node in BTC pay server, but you could use Zeus as your LSP.