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Lewy body disease can be detected before symptoms

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease.

A research group has now shown that the disease can be detected before symptoms appear, using a spinal fluid test.

Researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before other clear symptoms have developed.

#LewyBodies #neurodegeneration #olfaction

Addendae 4

Long COVID symptoms can emerge months after infection

* Long COVID can persist at least a year after acute illness passed, or appear months later

* for 16% of COVID-positive people symptoms last at least 1 year

* common for symptoms to resolve; re-emerge months later

* long COVID symptoms associated w. significant morbidity or reduced quality of life

Prevalence of Symptoms ≤12 Mo. After Acute Illness by COVID-19

#COVID19 #LongCOVID

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Addendae 5

COVID-19 causes mitochondrial dysfunction in heart, other organs

* mitochondrial genes can be negatively impacted by SARS-CoV-2 virus

* findings suggest new approaches for treating COVID-19

* Comment: I used to work in Bill Copeland's group at NIEHS; senior author Wallace (below) another leader in mt genetics

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent & human hosts

#COVID19 #LongCOVID #SARSCoV2