The way Pretty Good Apps functions right now:
You make a list called “mute list” (or “bot list” or “troll list” or “real people but I want to ignore them anyway” or heck, make ‘em all). She can now add profiles by hand to the list. And she can manage the list herself.
But the app also maintains a list of users that is managed by her WoT. The app automatically creates an attestation that translates: Alice endorses Bob as a curator of that list. So if Bob adds Zed to his list, then Zed will pop up on Alice’s list. And endorsements are transitive: if Bob endorses Charlie to curate the list, then Charlie will also influence Alice’s list.