Yes, absolutely. I'm mining on it with everything from a Bitaxe Ultra to an S21Pro (and via DATUM, so with my own block templates). A share is a share. It just takes longer to find a share with low hashrate.

If all you have is a Bitaxe, you'd want to set up lightning payments, which requires BOLT12.

If you have, say, an S9 or better, then on-chain is feasible. The minimum payout is normally ~1 million sats. But, if you stop mining to the account, you get a payout after all the shares have been rewarded as long as you have at least 65,536 sats.