There isn’t necessarily an “appropriate” response.
But simply dismissing the feelings as erroneous simply because they don’t fit with the “normal” deluded view of the world seems a little too convenient for the current system that exploits the shit out of us.
For many, the “midlife crisis” is the first time that we start to wake up from the carefully crafted dream world that we live in. The fact that it usually takes about 40 years to realize that something isn’t quite right is disturbing. Even more disturbing is that we are told that we are crazy the second any doubt starts to set in.