If you want to go hard at this, read these two books. Then you'll see where I come from with my disregard of "reality", and maybe some ideas that leave me with something more rewarding than nihilism.
The Case Agsinst Reality - Hoffman
Existential Psychotherapy - Yalom
Either one of these assumes you've been wandering down this path for a while, have some philosophy under your belt, maybe read Frankl, Kierkegaard, Jung, etc.
In some way it bring me back around to Mises and human action. Praxeology is pretty interesting, and even @knut svanholm's recent book is a good intro.
