Hey, do you mean your node with channels setup?

Usually 2-3 channels to major LSPs are enough, no ned to worry about balancing.

Or do you mean relay setup for your Nostr experience?

It (also) depends on how do you use it, we recommend 3-4 major ones (like Primal, Damus...), and some relay you trust that will keep your notes (maybe paid one? maybe your own)