It remains very unclear.

All of human history suggests that yes, this will happen. New generations forget the lessons taught by old generations and eventually fall into the same old traps. Bitcoin also still has some very real centralization risks over the timeframe of centuries, such as storing all the data required to be a full node.

However, part of the magic of Bitcoin that anyone can change it however they like. Any changes that make it worse, or make it “no longer Bitcoin” like removing the 21M supply limit or changing other fundamental aspects of the protocol like block size or block time won’t be adopted by everyone and will create failed network forks. Any changes that make it better only have to be demonstrated on a single node, and others can opt in over time to gain the benefits. Therefore it’s much easier for Bitcoin to get better rather than ever get worse.

Ultimately, the true value of Bitcoin is the shared UTXO set. Even if the network fails as currently constructed, or gets corrupted by ignorant future generations, I have a hard time seeing zero economic actors which store value in the UTXO set preserving it and recreating it in a new template which solves whatever issue arose to corrupt it in the first place. There will always be at least one node which remembers the purpose and function of Bitcoin, preserves the UTXO set, and reworks the network based around both of those elements.

So while history would suggest Bitcoin will eventually fail, I think it’s the best chance we’ve ever had at establishing a system of social organization which can truly transcend time and culture.