What is "fame" really? You can be famous and infamous. Fame is just a neutral descriptor of someone who surpassed Dunbar's Number, imo.
My only advice for handling fame I can offer is, I wouldn't worry about the responsibility of others, just follow your convictions and ideals as to what is morally right vs. wrong from your perspective. If you see a gross injustice occurring that you feel strongly about post about it and use your platform. Your followers have a brain and hopefully can think for themselves and either follow you or not on it.
The worst thing you can do when famous is worry about optics. People respect someone more who has flaws as they can relate. The idea and perception of Hollywood has put out there for the past 100 years of being "perfect" messes up breakout stars all the time as they're not ready as they are burdened by this pressure and they crack.
Humans have vices and flaws, no one is perfect. So just be yourself Poe let others decide on whether you want to be famous or not. Just act in accordance to your beliefs and never compromise them to appease someone.