There's definitely a fox that shows up from time to time in the backyard. That's the only daytime concern. Later night visits from neighborhood cat (maybe a threat to chickens?), skunks (no), opossum (no). Raccoons (?), too, but haven't seen any in a while.
Sounds like for longer trips I'd hopefully recruit a more willing / outdoorsy neighbor for at least a weekly check in and all the free eggs they care to take!