I think we will see all sorts of niche relays pop up and build a lot of voluntary grass roots communities like subreddits, Facebook groups, and forums, etc.
I think we will see communities who have been the most disenfranchised adopt it first. Political dissidents immediately come to mind. People who just want the truth and to be able to draw their own conclusions about medics/vaccines. People who want uncensored feeds.
Honestly, I think Nostr will act as the most powerful gateway to bitcoin adoption.