If the ability to create a bank run doesn't exist, then Bitcoin will suffer the same fate as gold. Individuals at least need a lightning channel to a bank node to have permissionless access to control majority of their wealth. This will protect against large scale fractional reserve banking.

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Agreed. Fractional reserved banking could be a death blow.

I was & still am concerned about that with the ETF’s. Fractional holdings in reserves changing percentages could significantly hurt BTC.