For me it was too much hassle for my threat model.

Install wasn't bad. Using an operating system like Qubes as your daily driver involves a multi-month period of learning and adjustment however.

Moving, copying, and pasting data between qubes is a bit tricky in certain instances, for example when using a password manager.

Software updates are a bit if a pain, as is doing things like setting up a wireguard VPN to pipe all your traffic through. Backup restore is pleasantly simple but it consumes a lot of space if you have a lot of application qubes.

Forget about playing most video games, the graphics capabilities and speed is simply not there.

Shoot for 32GB of RAM or more on host system, 64GB would be best.