I'm not recommending anything.
But I think it's certain that Bitcoin will forever appreciate against FIAT. So if your loan is hypercollateralized, BTC's declines are already predicted by the significantly higher collateral than the debt. The interest on this loan, of course, should be really low, considering the strength of the collateral.
That said, you keep your savings/assets in BTC while your debts remain in FIAT, which makes you richer over time, since FIAT loses value and BTC gains value.
More than the financial risk, the biggest problem here may be the custody risk, operationalizing this in a safe way is a big challenge.