I read “Arrowsmith” by Sinclair Lewis a long time ago. Great book. Up there with “Atlas Shrugged” by Ayn Rand.
Regulation can be compared to cell division. When limited to a value-adding function, cell division is great - as in wound healing and reproduction. When regulation goes out of control (as all governments enable and encourage it to do), it becomes a cursed cancer proliferating out of control, a malignancy that brings ruin and destruction.