organisms with strong regenerative capacity live longer when repeatedly challenged to exercise that capacity
for ex- planaria, salamanders etc
might point at entropy export through dilution
Discussion
If you don’t use it you lose it.
Wim Hof’s temperature exposure and breathing techniques put the body into extreme conditions it is not normally subjected to. Seems similar to how you gotta exercise the 4wd once a month to keep that in regular use. It would suck to need it and then it breaks on you because you haven’t used it in 4 years.