Yes, a Google Pixel phone purchased at Best Buy can be bootloader unlocked to run GrapheneOS, provided you buy the unlocked version. Users have successfully unlocked bootloaders on Pixel phones from Best Buy, similar to those from the Google Store, as long as they are not carrier-locked devices. Ensure that the device is marked as “unlocked” and avoid any carrier-locked models, particularly those from Verizon, which may have restrictions.