Thus far correlative evidence at best, but inflammation is indeed the enemy! More analysis and anti-establishment $$ need to go to research, but even a stroll thru the grocery store these days is encouraging.
Discussion
I am sorry. Please clarify what is encouraging? And why do you need more research to figure out seed oils are toxic?
Encouraging to see optionality and availability. (Non-gmo, affordable, organic etc)
They (PUFAs etc) are unstable, cause inflammation and their production indeed carries other toxic byproducts. I mean no long-term studies have been done comparing clearance from the body when replaced with more traditional fats (metabolism etc.) Fatty acids are persistent in the body as they make up lots of structure in the body.
The increase has been measured: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642429/