Replying to Avatar LukeoftheOzarks

There are a few people who do seem to be happy working nights. But the vast majority of people should not do it for any extended period of time. Even one or two nights a month disrupts your sleep for most of the month and keeps your bio rhythm dysregulated.

Second shift is a different matter in my opinion, and there are a good number of people who seem to adapt well to it.
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Not my name 2y ago

Indeed. It seems like it has a clear dose response relationship, like radiation.

No exposure is best, very limited exposure (like second shifts or late shifts) may be tolerable, but extended exposure (involving frequent switching back and forth from day/night schedules, or years of shift work) is just plain terrible for you from a physiologic standpoint.

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Not my name 2y ago

I personally find the research into how cellular and dna repair mechanisms are dependent on the melatonin sleep/wake axis most convincing and concerning.

That is to say nothing about all the other practical ways in which working nights can be disruptive.