Yes, it's not 100% secure, but these mitigation practices definitely works. The more best practices you follow, the more expensive it becomes to exploit.
Even with native applications, governments literally pay billions of dollars for spyware named Pegasus, which can access your phone and they just have to send you a text DM.
But if you're asking whether it's secure enough to create a nostr clients and note app, I can assure you that it is. In fact, I believe it's even more capable than that.
But I also understand where you are coming from.