Saylor is speaking to major institutions, not individuals. His audience is corporate, and they aren't interested in the ideals of personal financial autonomy. While small businesses and individuals can use hardware wallets for self-sovereignty, large organizations—such as corporations, pension funds, and wealth funds—require centralized custody solutions.

Whether you accept it or not, this is the reality. For them, Bitcoin-friendly banks with centralized custody services are a necessity unless managing custody themselves is part of their core operations.