Overall there seems to be a continued growing trend of data the patients do better with combo medication versus a single medication to treat high blood pressure.

Among adults living in India with elevated BP, three different dual-medication polypills containing combinations of recommended first-line antihypertensive agents effectively lowered ambulatory BP, researchers reported.

Data from TOPSPIN, a randomized, three-arm trial of single-pill combinations of a renin-angiotensin system inhibitor, a long-acting ACE inhibitor and a thiazide-type diuretic, also demonstrated that the three combinations were equally effective across groups in a South Asian population, where there remains an outsize hypertension burden.