Different CPU.

Original one got fucked up.

5000 series Ryzen wouldn't power up. Needs BIOS update for it.

4000 series, same deal.

Got a cheap 3000 series. Motherboard finally makes it through POST, but then the BIOS screen comes up and nothing happens.

This motherboard is the only Asus motherboard I've ever had that doesn't have a BIOS flashback port on the IO panel so you have to load an operating system and use an app to update the BIOS.