Start with the obvious:

Have strong self custodial keys and passphrase

Use offline signing device

Consolidate or manage uxtos

Use good seed plates and test recovery

Don't keep seed plate and phrase plate in same place or at your home

Have a second out of home backup in a different state

Are you one robbery or warrant away from seizure

Keep recovery plan for family outside of home in secure location

Use encrypted drives, strong passwords and password managers