100%. I had a weird condition for years where any skin exposed to cold (especially damp cold) when I came back inside all that skin would be red, itchy, hot wherever it was exposed. Usually hands and face.
But it was so DISTINCT, if I wore short sleeves, arms would be red, shoulders would be fine and with a clear line of demarcation where the sleeve ended. So bad that if I wore a V Neck, it would leave a red V.
No way debilitating but just consistently annoying for someone who always loved the cold weather.
I've been waiting to believe it actually was gone, but after a couple weeks in the 20°s here I'm comfortable and confident to say that after a couple decades, and issue that my doctor said was 'the damnedest thing' and had NO clue as to how to deal with, is no longer an issue.