One Flew Over the Cuckoo's Nest is a 1975 American psychological comedy-drama film[4] directed by Miloš Forman, based on the novel by Ken Kesey. The film stars Jack Nicholson as a new patient at a mental institution and Louise Fletcher as the domineering head nurse. Will Sampson, Danny DeVito, Sydney Lassick, William Redfield, Christopher Lloyd and Brad Dourif play supporting roles, with the latter two making their feature film debuts.