Here's some signal:

- coffee is somewhere between a seed/bean soup as far as your gut is concerned

- the mycotoxins and molds in coffee are cumulative; small doses add up over decades.

- raised blood pressure is never a benefit

- anxiety/shakiness are real effects

- caffeine interfers with our own brain's circadian rythm management

- dependency and withdrawal are signs it's not healthy

I like coffee, but I've noticed these effects add up over time and stress the body.