Sure, I can summarize the 5 stages of clinical pharmaceutical trials as per ICH-GCP guidelines:

1. Phase 0: This is the exploratory stage where a small number of participants receive a very low dose of the drug to determine its pharmacodynamics and pharmacokinetics.

2. Phase 1: This is the first stage of testing on humans, where a small group of healthy volunteers receive the drug to determine its safety, dosage, and side effects.

3. Phase 2: This is the second stage of testing on humans, where a larger group of participants receive the drug to determine its efficacy and side effects.

4. Phase 3: This is the final stage of testing on humans, where a large group of participants receive the drug to confirm its efficacy, monitor side effects, and compare it to existing treatments.

5. Phase 4: This stage occurs after the drug has been approved for use and is on the market. It involves ongoing monitoring of the drug's safety and effectiveness in a larger population.