For sure. I think there is a cross-over for custom views, and possible add mute rules to a specific view. A view could include one or many lists - and perhaps media type selection.

By organising are you thinking about views, or local virtual folders, or something else.

One of my main concerns atm is new users starting with few relays, no following suggestions, and ending up in global - which is a bit of the Wild West - as it should be; but with filters.