How the heck can I “mute” all this spam in the global feed? Are there specific relays to turn off or anything else I can do?
Discussion
I believe you’ll be able to filter the global feed by specific relays in a future Damus update. Other clients may support it too.
You can try using Iris client which does some filtering. Or remove public relays & add paid relays like Wine + Wine Filter which broadcasts and pulls from public relays.