Yes but you get yourself into bit of a logic loop.
Say you determine that Bitcoin is the best place for your capital & it's going to outperform 10% pa over 5 years.
Why would you borrow to start a business when you could just borrow to buy more Bitcoin?
There's risk in a Bitcoin backed loan, but if you're going that way anyway, why wouldn't you just go harder?
It's an interesting thought experiment.
I've been tempted to start a lawn mowing or gutter cleaning service. It requires a very low initial capital outlay & is labour intensive. Perfect for me.
Window washing is another example.
They're shitty jobs that need to be done. There's also generally little competition if you provide a decent service.