Before I start proposing solutions like all the posts above, a few additional questions:
1. Is it a lot or a little?
2. What has been the trend over the last week/30 days?
3. Does the Damus relay have any purging/archiving mechanism implemented?
4. What effect does database size have on relay performance?
5. Is the relay architecture scalable?
Do you want to write a longer article about the operation of Damus relay? Many of us would welcome it!