That's pretty much what I'm thinking about, in the short term.
Be born in carbon-replicator form, then upload your ass to a silicon-binary form than can withstand gamma rays, extreme cold, enormous time lapses, and all that nasty crap that you need to endure in order to star-hop at sublight speeds.
But eventually, I think the whole "being born" thing ceases to make sense or just becomes impossible, and we just stick to inorganic, voluntarily or not.