My daily OPSEC doesn't call for such extreme measures. If I need to use a multi-hop VPN setup, I will for specific usecases. I would rather not take the speed hit unless I have to. I also use and recommend Whonix over Tor. The baked-in integration with QubesOS + disposable VMs is good stuff.
Discussion
I also wonder how much it really adds. If one of the top 5 privacy VPNs is a honeypot, why not all 5? Defence in depth i suppose.
I've been thinking about moving to NixOS but I've got so uses to the piece of mind I get from using disposable Whonix VMs. This looks promising though: https://forum.qubes-os.org/t/starting-work-on-nixos-template/25591/21