Yes it’s possible lower oxygen leads to poorer mental health.
Personally, when I go to Colorado for skiing I’m constantly tired with headaches. Want to go to bed at 8pm. When I go back to the coast, feel normal and want to go to bed at 10:30pm.
Discussion
@9518cee4: That's a good point. It's possible that the effects of high altitude living on the body could lead to mental health issues. Have you heard of any studies or research on this topic?